You may report side effects to FDA at 1-800-FDA-1088. Comfrey cream, an topical herbal product, is thought to reduce inflammation and pain when applied to the skin. This is not recommended due to the presence of chemicals that can cause organ damage and cancer. For one of these studies, the average time participants had experienced knee pain and stiffness leading up to the study was six and a half years! 2 Comfrey cream contains several active components (substances). This is done by soaking the root in at least 50% alcohol for a minimum of two weeks. Regul Toxicol Pharmacol. Check regularly, but it should take about six weeks for all the leaves to break down into a thick, black liquid. While larger and more studies are needed to fully determine safety and effectiveness, short term topical application of comfrey may give you peace of mind, relief, and support while you rest and heal, following any additional advice from your physician. What alternatives to comfrey cream are there for back pain? 1.35 Fl Oz. Verywell Health's content is for informational and educational purposes only. More research is needed. Scientific studies have shown comfrey oil can help reduce the likelihood leg ulcers will become infected.7, Topical application of comfrey oil has been shown to support the lower and upper back more than methyl nicotinate, the main ingredient in many muscle creams.8. Registered office: Samuel Ryder House, Barling Way, Nuneaton, Warwickshire CV10 7RH. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. Kucera, M., Kalal, J., and Polesna, Z. Choose organically grown comfrey when possible. Laslett, L. L., Quinn, S. J., Darian-Smith, E., Kwok, M., Fedorova, T., Korner, H., Steels, E., March, L., and Jones, G. Treatment with 4Jointz reduces knee pain over 12 weeks of treatment in patients with clinical knee osteoarthritis: a randomised controlled trial. Topical preparations of comfrey are generally safe provided they are not applied excessively or to an open wound. Its ready when the mixture has solidified somewhat and has a cloudy, creamy, and slightly runny consistency. The plant leaves have a lower concentration of PAs than the roots. Using a supplement like comfrey may have potential side effects. Some people ingest comfrey roots or leaves or use them in teas. This item: Terry Naturally Traumaplant Comfrey Cream - 1.76 oz (50 g) - Non-Staining Topical Botanical, Free of Toxic Pyrrolizidine Alkaloids (PAs) & Parabens - for External Use Only $20.76 ($11.80/Ounce) Dr. Christopher's Comfrey Ointment, 2 Ounce $11.99 ($6.00/Ounce) Dr Christopher's Formula Complete Tissue and Bone Ointment, 4 Ounce Some medications can also harm the liver. 2013;163:5864 (2013) doi:10.1007/s10354-012-0162-4, Giannetti BM, Staiger C, Bulitta M, Predel HG. These have a lower risk of serious side effects like liver damage. Comfreycontains PAs, substances that can cause significant damage, including: Therefore, it should never be taken by mouth. Amazon.com: Comfrey Cream View abstract. View abstract. View abstract. Comfrey's original name, knitbone, derives from the external use of poultices of its leaves and roots to heal burns, sprains, swelling, and bruises. Osteoarthritis.Cartilage. Comfrey is traditionally used for the symptomatic treatment of minor sprains and bruises and is also known for its healing properties. Barna, M., Kucera, A., Hladicova, M., and Kucera, M. [Wound healing effects of a Symphytum herb extract cream (Symphytum x uplandicum NYMAN: ): results of a randomized, controlled double-blind study]. This could change the effects and side effects of comfrey. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use. Comfrey is traditionally used for the symptomatic treatment of minor sprains and bruises and is also known for its healing properties. This is done by soaking the root in at least 50% alcohol for a minimum of two weeks. 2010;73(2):97-100. Be sure to use comfrey root from a reputable source that has properly identified the species. Contact your doctor or pharmacist if you have any questions before use. Read our. This leads to cirrhosis and eventually liver failure. June 3, 2022 Posted by: Category: Uncategorized; No Comments . Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Influence of moderate physical exertion on subacute low back pain, after Symphytum officinale ointment treatment. Tunon, H., Olavsdotter, C., and Bohlin, L. Evaluation of anti-inflammatory activity of some Swedish medicinal plants. An Evidence-Based Reference. The efficacy and safety of a homeopathic gel in the treatment of acute low back pain: a multi-centre, randomised, double-blind comparative clinical trial. Herb & Supplement Guide. Can a comfrey (Symphytum officianale) root extraction help ease aching joints and muscles? Lewis, C. J. FDA Advises Dietary Supplement Manufacturers to Remove Comfrey Products From the Market. Rad. NIH Office of Dietary Supplements. Turley, A. J. and Muir, D. F. ECG for physicians: a potentially fatal case of mistaken identity. This is because only a small amount of the pyrrolizidine alkaloids are absorbed through the skin (Jedlinszki et al., 2017). Amendments to the poison list. Comfrey - Memorial Sloan Kettering Cancer Center However, even if supplements are third-party tested, that doesn't mean they are necessarily safe for all or effective in general. Swiss.Med.Wkly. Influence of moderate physical exertion on subacute low back pain, after Symphytum officinale ointment treatment. British Homeopathic Journal, 90(01), 21-28. https://doi.org/10.1054/homp.1999.0460. The ointment has a very mild herbal fragrance and is soothing on application. The combination of Vitamin E, Wheat Germ oil and Rice Bran oil makes this cream perfect for your daily hydration needs. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Bird Flu Deaths Prompt U.S. to Test Vaccine in Poultry, COVID Treatment in Development Appears Promising, Marriage May Help Keep Your Blood Sugar in Check, Getting Outdoors Might Help You Take Fewer Meds, New Book: Take Control of Your Heart Disease Risk, Getting Help for a Loved One With Psychosis: It's Complicated, Health News and Information, Delivered to Your Inbox, Vitamins and Supplements to Avoid with Hepatitis C. With extract of Comfrey. This site uses cookies to improve your experience. Whenselecting a brand of supplements, look for products certified by Consumer Labs, the U.S.Pharmacopeia, or NSF. Hybrids and other species may have a similar appearance but could have significantly different amounts of the toxic pyrrolizidine alkaloids (Kucera et al., 2018). Comfrey. Book your free, one-to-one online consultation with one of our qualified advisors. Thank you, {{form.email}}, for signing up. (2004). After the tincture is made, then you can whip up the fabulous joint and muscle cream! However, further well-designed studies are needed. Herbal medicine for low back pain: A Cochrane review, Dietary Supplements: What You Need to Know, Sinusoidal obstruction syndrome (blockage of veins in the liver). Symphytum species: A comprehensive review on chemical composition, food applications and phytopharmacology. Staiger, C. Comfrey root: from tradition to modern clinical trials. Tolerability and effectiveness of an antitrauma cream with comfrey herb extract in pediatric use with application on intact and on broken skin. The way that they work is by blocking small blood vessels in the liver. Pyrrolizidine poisoning. These side effects may be common or severe. In a study of 712 children with superficial wounds, applying a 25% comfrey cream for one week or up to two weeks (2-4x day) offered a strong benefit to risk ratio (Kucera et al., 2018). Facebook; Twitter; Pinterest; Related Posts. Comfrey Uses, Benefits & Side Effects - Drugs.com Herbal Database Comfrey is generally considered unsafe, with numerous toxicological effects in animals and humans. Like any new treatment, discontinue use if any irritation occurs. Medicine makers would bind comfrey leaves and roots in poultices, then apply those poultices to the skin to treat injuries. Its long, lance-shaped leaves can be up to 1 foot in length closer to the bottom of the stem and are shorter higher up the stem. Inhibition of prostaglandin biosynthesis and PAF-induced exocytosis. To make this recipe, first, you must prepare the comfrey root tincture. Cochrane Database Syst Rev. First, make the comfrey root tincture by combining the dried comfrey root and alcohol in a sterilized, dry, glass pint jar. 1/8 cup comfrey tincture (Symphytum officinale), store bought or via recipe, above. To reduce the risk of side effects, never apply comfrey cream to broken skin or open wounds as it may be more highly absorbed by the body. A member of the borage family, comfrey root, leaves, and stems have an obvious coat of bristly hair. Its long, lance-shaped leaves can be up to 1 foot in length closer to the bottom of the stem and are shorter higher up the stem. Comfrey shouldn't be used in any form during pregnancy or nursing due to the risk of liver damage to infants. Efficacy and safety of topically applied Symphytum herb extract cream in the treatment of ankle distortion: Results of a randomized controlled clinical double-blind study. The roots and leaves of the comfrey plant have medicinal properties. randomized double-blind study of 278 patients with fresh abrasions, a. topical preparation containing a 10% comfrey leaf extraction applied for 2-3 days reduced wound healing time of adults and children without side effects (Barna et al., 2012). Comfrey oil should be applied topically to parts of the body where you have muscular pain or discomfort. Efficacy and tolerance of a comfrey root extract (Extr. Skip the missed dose if it is almost time for your next scheduled dose. Beth Thomas, PharmD, is a clinical pharmacist and founder of BMT Consulting Services, LLC. J Ethnopharmacol 1995;48(2):61-76. View abstract. 2013;27(6):811-7. The Food and Drug Administration (FDA) released an advisory in July 2001 recommending that comfrey products be removed from the market because of cases of hepatic veno-occlusive disease. Additionally, because its alkaloids are absorbed through the skin, use of comfrey as a poultice should not exceed an exposure of 100 mcg/day of the alkaloids. Effects of Symphytum ointment on muscular symptoms and functional locomotor disturbances. Comfrey is considered likely unsafe to use if you are nursing a baby. Complement Ther Med. Comfrey has been used medicinally for at least 2000 years for various conditions, including bone fractures, ulcers, and gout. Be sure to choose organic carrier oils and essential oils when possible. Jurcu, R., & Jurcu, I. 2012;101(4):211-216. Transfer the cooled oil and butter mixture to a standing electric mixer or blender. Toxicol Lett 2005;155:411-20. Phytomedicine, 14(1), 2-10. https://doi.org/10.1016/j.phymed.2006.11.006, Jedlinszki, N., Balzs, B., Csnyi, E., & Csupor, D. (2017). A review of 26 clinical trials concluded that mild skin reactions were the most common side effects of comfrey creams used in the studies. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Terry Naturally Traumaplant Comfrey Cream - amazon.com Phytomedicine 2005;12(10):707-714. COMFREY: Overview, Uses, Side Effects, Precautions - WebMD J Toxicol Environ Health B Crit Rev. 2008;54(1):7-20. For External Use only Do not use if you are sensitive to any of the ingredients. Efficacy and safety of comfrey root extract ointment in the treatment of acute upper or lower back pain: Results of a double-blind, randomised, placebo controlled, multicentre trial. Efficacy of a comfrey root extract ointment in comparison to a Diclo-fenac gel in the treatment of ankle distortions: Results of an observer-blind, randomized, multicenter study. 1 It's found in Europe, Asia, and North America. Jedlinszki N, Balzs B, Csnyi E, Csupor D. Penetration of lycopsamine from a comfrey ointment through human epidermis. , meaning to grow together. Symphyti) bei Sprunggelenks-distorsionen. Smith DB, Jacobson BH. (2018). New South Wales Health, Australia. Potters Comfrey Oil | Holland & Barrett Shop our range of Potter's Herbals products at Holland & Barrett, including Potters Comfrey Oil. Patients with hypersensitivity or allergic reactions to the plant should also avoid external use. Credit Solution Experts Incorporated offers quality business credit building services, which includes an easy step-by-step system designed for helping clients build their business credit effortlessly. A critical scoping review of external uses of comfrey (Symphytum spp.). (2013). Comfrey may also be used for purposes not listed in this product guide. https://doi.org/10.1007/s10354-007-0474-y. 1. 12 drops peppermint (Mentha piperita) essential oil Comfrey is often sold as an herbal supplement. HOLLAND & BARRETT PRO VITAMIN E DAY CREAM 50ML This Vitamin E day cream works with your skin daily to hydrate and protect your skin. Study results revealed that pain intensity during active movement decreased an average of 95.2% in the group given comfrey ointment. For topical comfrey cream, look for products labeled as free of pyrrolizidine alkaloids. They help us to understand how people use the website and give us the ability to provide targeted marketing to you. Healthy adults: massage about 1 teaspoon of cream into a local area up to 4x/day for up to 2 weeks. There are no regulated manufacturing standards in place for many herbal compounds and some marketed supplements have been found to be contaminated with toxic metals or other drugs. It is easily absorbed to leave your skin feeling fresh, soft and radiant. What is niacinamide? When harvesting comfrey or buying from a non-commercial supplier, note that there is variety within the species. Comfrey has been cultivated as a green vegetable and has been used as an herbal medicine for more than 2,000 years. We currently have no information for COMFREY overview. Mackinnon, M. In general practice, 'always expect the unexpected'. This makes quite a thick rich cream good for a body cream and an all healing cream . The FDA has recommended that all comfrey products that are taken by mouth be removed from the market. Comfrey: Soothes Muscles & Joints + Helps Relieve Pain - Dr. Axe View abstract. Documented adverse effects (the pyrrolizidine alkaloids, have substantial risk of causing fatal liver damage and can cause abortion). Our website is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Comfrey contains chemicals that cause serious liver damage when taken by mouth. Comfrey has long been used in folk traditions for bruising and abrasions. of India and by a State Level Environment Impact Assessment Authority constituted by Government of India on the recommendations made . The participants were assigned three weeks of treatment with two grams of either comfrey ointment or a placebo three times a day. Comfrey ( Symphytum officinale) is an attractive ornamental plant used in gardening and medicine. Wound-healing effects of a symphytum herb extract cream (. This includes androstenedione, bishop's weed, borage, chaparral, comfrey, DHEA, echinacea, garlic, germander, golden ragwort, hound's tongue, kava, licorice, niacin (vitamin B3), pennyroyal oil, red yeast, St. John's wort, and others. As a Licensed Massage Therapist for fifteen years, I have noticed that back pain can be caused by a variety of reasons and can be very debilitating. Pabst H, Schaefer A, Staiger C, Junker-samek M, Predel HG. Do not use comfrey with very young children or during pregnancy or lactation. Add cup of the comfrey tincture and all essential oils to the cooled oil/butter mixture. Bagheri Z, Azizi A, Oshvandi K, Mohammadi Y, Larki-Harchegani A. (2013). Br.J Sports Med. View abstract. J Pain. Available for Android and iOS devices. CBD oils being bought in high street stores such as Boots and Holland & Barrett are weak, low quality and don't provide the actual therapeutic advantages. Modern science suggests that the ancients were correct in believing comfrey helps to heal woundsand relieve pain.3,4 In this article, well explain where comfrey comes from, comfrey oils remarkable health benefits and how to use it at home. Scoop the finished comfrey cream into sanitized glass jars. Instructions. Comfrey might harm the liver. What Are the Side Effects of Comfrey Cream? Generic name: comfrey [COM-free] Comfrey: ancient and modern uses. View abstract. This recipe is contraindicated for small children and those with certain medical conditions. doi:10.1002/ptr.4612, Salehi B, Sharopov F, Boyunegmez Tumer T, et al. Glass bowl with a lid Preclinical studies suggest that oral comfrey has antiproliferative effects , and a topical formulation showed wound healing properties . View abstract. Wien Med Wochenschr. Additionally, use on a deep cut may encourage healing of the outer skin the preparation comes in direct contact with faster than the deeper tissue, leading to abscess. It also came as a reference to the belief that comfrey can mend broken bones. This is not a complete list of side effects and others may occur. 16 Rewards for Life points with this purchase. Comfrey flowers are bell-shaped and purple, pink, or pale yellow in color, and it has a dark taproot. View abstract. Koll, R., Buhr, M., Dieter, R., Pabst, H., Predel, H. G., Petrowicz, O., Giannetti, B., Klingenburg, S., and Staiger, C. Efficacy and tolerance of a comfrey root extract (Extr. Roeder E. Medicinal plants in Europe containing pyrrolizidine alkaloids. Because of the risk of liver toxicity, comfrey cream shouldn't be used with other medicines that may also cause liver damage. The Comfrey Controversy: Can and Should One Use Comfrey Internally? Further study is needed to confirm these results. Please read the Topical Use Safety section of this article (above) before using. These include allantoin, rosmarinic acid, and others. Comfrey oil is a herbal oil that moisturises skin, and that's been used as a healing herb for a long time. View abstract. What are the benefits of using it? Avoid comfrey with certain medical conditions, such as liver disease. A handbook for practice on a scientific basis. Spine(Phila Pa 1976). Many of those following the folk use of comfrey up to present-day think so. The efficacy and safety of comfrey. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. After testing their 1000mg CBD oil drops for over a month, we now have little question this is the best CBD oil within the UK as of 2019. This information may not fit your specific health circumstances. Journal of chiropractic medicine, 10(3), 147-156. https://doi.org/10.1016/j.jcm.2011.01.003, Stam, C., Bonnet, M. S., & van Haselen, R. A. Of course, more research is needed to validate efficacy and safety. Comfrey has been claimed to heal gastric ulcers and hemorrhoids, and to suppress bronchial congestion and inflammation. Understand comfreys contraindications before using it. Regarding its antioxidant, antilipoperoxidant, antiinflammatory, and cytotoxic properties. Comfrey is traditionally used for the symptomatic treatment of minor sprains and bruises and is also known for its healing properties Customer Reviews Ingredients Full ingredients Brassica Campest is Seed Oil (Rapeseed Oil), Symphytum Officinale Herb (Comfrey Herb), BHA, Eucalyptus Globulus Leaf Oil (Eucalyptus Oil). (2004). We comply with the HONcode standard for trustworthy health information. It should only be used in small amounts for short periods as a cream. comfrey cream holland and barrett - mail.empower.tn View abstract. Phytomedicine, 12(10), 707-714. https://doi.org/10.1016/j.phymed.2005.06.001, Smith, D. B., & Jacobson, B. H. (2011). Select a condition to view a list of vitamins. cbd cream holland and barrett for pain relief byBhupesh Panchal, Senior Regulatory Affairs Associate, Comfrey oil is a herbal oil that moisturises skin, and thats been used as a healing herb for a long time.1, Since at least the 4th century, people have used comfrey medicinally. Call your doctor if the condition you are treating with comfrey does not improve, or if it gets worse while using this product. FDA Advises Dietary Supplement Manufacturers to Remove Comfrey Products From the Market. Do not take comfrey without medical advice if you are using any of the following medications: This list is not complete. And topical capsaicin cream may help to relieve pain temporarily. The internal or extensive topical use of comfrey cannot be recommended because of numerous reports of liver damage. When the root is boiled in water, it forms a sticky, glue-like paste. 2013;21(6):724-45. 2013;5(5):CD010538. Company number 02758955 Registered VAT number 211727395. Comfrey has been used in alternative medicine as a possibly effective aid in treating back pain, osteoarthritis, or tenderness and swelling caused by a sprain injury. Results of an observational study of patients]. ). Heard about essential oils but not quite sure about what they can do for you? She is passionate about providing evidence-based recommendations that make health decisions easier and improve lives. Phytomedicine. WMW Wiener Medizinische Wochenschrift, 154(21), 498-507. https://link.springer.com/article/10.1007/s10354-004-0114-8, Natural Medicines (2020). Consult your healthcare provider before using. Osteoarthritis Cartilage. As we are constantly reviewing and developing our products to meet our consumer needs, consumers, particularly those that suffer from allergies and intolerances, should always check product labelling, warnings, and directions provided with the product that is delivered, prior to use or consumption. Drug class: Herbal products. Need some help with an order or want to speak to a member of our Customer Services team? Learn more in. . 2758955. Penetration of lycopsamine from a comfrey ointment through human epidermis. radix) extract ointment in the treatment of patients with painful osteoarthritis of the knee: results of a double-blind, randomised, bicenter, placebo-controlled trial. You and your healthcare provider should weigh the pros and cons and use it only under their supervision. Herbal drugs and phytopharmaceuticals. 2010;13(7-8):509-526. doi:10.1080/10937404.2010.509013, Staiger C. Comfrey: A clinical overview. Penetration of lycopsamine from a comfrey ointment through human epidermis. Efficacy and tolerance of a comfrey root extract (Extr. Cbd Oil In Holland And Barrett. Medicinal use of this product has not been approved by the FDA. 2012;26(10):14411448. Be sure to choose organic carrier oils and essential oils when possible. 2014;20(4):347-55. Phytomedicine, 11(6), 470-477. https://doi.org/10.1016/j.phymed.2004.02.001, Kucera, A., Barna, M., Holcova, S., Horacek, O., Hladikov, M., & Ottillinger, B. Comfrey cream combines ingredients like oils or water and glyceryl stearate with Symphytum officinale (comfrey) extracts. Efficacy and safety of comfrey root extract ointment in the treatment of acute upper or lower back pain: results of a double-blind, randomised, placebo-controlled, multicentre trial. Nat Prod Res 2018;32(5):605-9. doi: 10.1080/14786419.2017.1326492. If you're considering using the cream, consult your healthcare provider first. Centurian, South Africa: Medpharm Scientific Publishers. Bleakley, C. M., McDonough, S. M., and MacAuley, D. C. Some conservative strategies are effective when added to controlled mobilisation with external support after acute ankle sprain: a systematic review. View abstract. It is called knitbone or boneset, referring to the bone-like growth of its roots. No comments. Kucera, M., Barna, M., Horacek, O., Kalal, J., Kucera, A., and Hladikova, M. Topical symphytum herb concentrate cream against myalgia: a randomized controlled double-blind clinical study. View abstract. Ther Drug Monit 2001;23:698-708. The Pharmaceutical Journal, PJ, December 2007. Z Phytotherapie 2000;21:127-134. As the consistency thickens some more, turn the mixer up a little bit more. To make the cream, combine sunflower oil, safflower oil, coconut oil, and cocoa butter in a double-boiler over low heat until completely melted. Knit bone, Eucalyptus, Rapeseed Oil, BHA. It contains chemicals that are poisonous. Available for Android and iOS devices. Hepatology. This site uses cookies to improve your experience. Links to external sites are for informational purposes only. All rights reserved. Rad. Predel, H. G., Giannetti, B., Koll, R., Bulitta, M., & Staiger, C. (2005). Looks like you may need to upgrade your browser We're sorry, we no longer support the web browser that you are using Additionally, there is scientific research demonstrating comfreys effectiveness at soothing muscle and joint pain, some of which are highlighted in this post. A later study of 133 peoplefound some evidence that a topical combination of comfrey extract and tannic acid led to reduced knee pain. The chemicals contained in comfrey may cause birth defects. Aust.J Physiother. Koll R, Klingenburg S. [Therapeutic characteristance and tolerance of topical comfrey preparations. The ankle swelling decreased by 79.5% in the comfrey root group and 69.4% in the diclofenac group. 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